THE HYPOXIA-DRIVEN CROSSTALK BETWEEN TUMOR AND TUMOR-ASSOCIATED MACROPHAGES: MECHANISMS AND CLINICAL TREATMENT STRATEGIES

The hypoxia-driven crosstalk between tumor and tumor-associated macrophages: mechanisms and clinical treatment strategies

Abstract Given that hypoxia is a persistent physiological feature of many different solid tumors and a key driver for cancer malignancy, it is thought to be a major target in cancer treatment recently.Tumor-associated macrophages (TAMs) are the most abundant immune cells in the tumor microenvironment (TME), which have a large impact on tumor develo

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Numerical inverse Laplace transform based on Bernoulli polynomials operational matrix for solving nonlinear differential equations

A numerical inverse Laplace transform method is established using Bernoulli polynomials operational matrix of integration.The efficiency of LADIES SKIRT LEATHER the method is demonstrated through some standard nonlinear differential equations: Duffing equation, Van der Pol equation, Blasius equation and jerk equation.The solution approach is to ado

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